Work

2025–now
Bioinformatician
Department of Clinical Genetics, Erasmus MC
- Production data pipelines in an ISO 15189-accredited laboratory
  I build and validate the pipelines that process patients' sequencing data:
  - A Nextflow pipeline for nanopore long-read sequencing
  - Nextflow pipelines for polygenic scoring
  - Validations for DRAGEN processing of short-read data
  - Ultrarapid diagnostics for critically ill children, EJHG 2025
- Infrastructure and tooling for the team
  I take on sysadmin and DevOps tasks for the team:
  - GitLab CI components for pre-commit hooks, static code analysis and git-flow
  - Administration of the PromethION data towers (Ubuntu), and first on call when they fail
  - Reports and exploratory work for compute and storage planning
2021–2025
Postdoctoral researcher
Department of Clinical Genetics, Erasmus MC
- Cross-trait genetics: methods, software and studies
  I developed methods and software for finding genetic variants shared between traits:
  - SumRank, a new method, and a benchmark of it against the existing ones
  - ctar, an R package with standardised versions of these methods, with continuous integration and test coverage
  - Two cross-trait studies that I initiated and supervised: acne and inflammatory bowel disease (Journal of Investigative Dermatology, 2026), and the cortex and six psychiatric disorders (preprint, 2026)
  - ctar, the R package
  - The benchmark, medRxiv 2025
- Three MSc courses, developed and run every year · 2022–2025
  I ran courses for the Genomics in Society MSc:
  - Developed and coordinated Statistics for Genomics
  - Co-developed and co-coordinated Research Design and part of Genomics and the City
  - Built statistics4genomics, a website of R-programming puzzles that is the capstone of Statistics for Genomics
2016–2021
PhD candidate
Department of Epidemiology, Erasmus MC
- QDECR: open-source MRI analysis at cohort scale, in R · since 2018
  From an idea by Ryan Muetzel, I built QDECR, an R package for large-scale analysis of structural MRI data with R's own formula syntax. I still maintain it.
  - The paper, Frontiers in Neuroinformatics 2021
  - qdecr.com
- ORACLE: data collection for nearly 2,000 parents, from protocol to ETL · 2017–2019
  I set up ORACLE, a brain-health study within Generation R, and ran it for the bulk of its data collection:
  - Adapted the protocol, wrote all the SOPs and did the ethics amendment
  - Trained all the students and staff
  - Wrote the automated quality-control pipeline for its data (ETL)
  I am first author of its design paper.
  - The design paper, European Journal of Epidemiology 2021
- MRI data collection in a population cohort, with automated quality control · 2016–2018
  I led the first part of Generation R's third wave of neuroimaging, which scanned some 3,000 children in all:
  - Wrote part of the protocols and helped train the students and staff
  - Wrote the code for automated quality control of the MRI data
  - Coordinated the procedure for incidental findings